Increasingly, modern organic synthesis is driven by the pursuit of function, as evidenced in two of its central research endeavors, total synthesis and methods discovery and development. In complex natural product synthesis, the ideal target is not only architecturally fascinating, but also exhibits potentially useful medicinal properties toward which an efficient synthesis could provide useful quantities for further biological studies. Similarly, in reaction discovery and development, the new method ideally facilitates the efficient synthesis of motifs prevalent in medicinal or functional compounds and materials.
Our research group seeks to address difficult but rewarding fundamental problems in both synthesis and technology development, such as the synthesis of quaternary stereocenters and selective C-H functionalization. Ultimately, we hope our endeavors will further the ideals of modern organic chemistry: advancing the field from a basic science perspective while also lending to numerous applications in biomedicine and materials science.
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